check navigate-up navigate-left navigate-right expand
Book with Confidence Guarantee™
Comprehensive payment protection
Customer service available 24/7
Welcome to the new VacationRentals.com! Use the new filters and search options to find your next vacation rental.

James Island Vacation Rentals (103)

  • 1 - 50 of 103
    • 1 BR
    • 1 BA
    • Sleeps 2
    10

    Confirmation within 24 hours

    Your booking request will be confirmed or denied within 24 hours.

      $244
      avg/night
      • 2 BR
      • 1 BA
      • 1 HF BA
      • Sleeps 4
      67

      Confirmation within 24 hours

      Your booking request will be confirmed or denied within 24 hours.

        • Studio
        • 3 BA
        • Sleeps 9
        1 Review

        Confirmation within 24 hours

        Your booking request will be confirmed or denied within 24 hours.

          • 4 BR
          • 4 BA
          • 1 HF BA
          • Sleeps 12
          2 Reviews

          Confirmation within 24 hours

          Your booking request will be confirmed or denied within 24 hours.

            • 4 BR
            • 4 BA
            • Sleeps 12
            9

            Confirmation within 24 hours

            Your booking request will be confirmed or denied within 24 hours.

              • 5 BR
              • 3 BA
              • 1 HF BA
              • Sleeps 12
              31

              Confirmation within 24 hours

              Your booking request will be confirmed or denied within 24 hours.

                • 4 BR
                • 4 BA
                • Sleeps 8
                10
                  • 3 BR
                  • 2 BA
                  • 2 HF BA
                  • Sleeps 10
                  1 Review
                    • 3 BR
                    • 2 BA
                    • Sleeps 8
                    17

                    Confirmation within 24 hours

                    Your booking request will be confirmed or denied within 24 hours.

                      • 2 BR
                      • 2 BA
                      • Sleeps 6
                      20

                      Confirmation within 24 hours

                      Your booking request will be confirmed or denied within 24 hours.

                        • 4 BR
                        • 2 BA
                        • Sleeps 10
                        13
                          • 2 BR
                          • 2 BA
                          • Sleeps 6
                          12

                          Confirmation within 24 hours

                          Your booking request will be confirmed or denied within 24 hours.

                            • 4 BR
                            • 3 BA
                            • 1 HF BA
                            • Sleeps 10
                            7

                            Confirmation within 24 hours

                            Your booking request will be confirmed or denied within 24 hours.

                              • 2 BR
                              • 1 BA
                              • Sleeps 8

                              Confirmation within 24 hours

                              Your booking request will be confirmed or denied within 24 hours.

                                • 3 BR
                                • 2 BA
                                • Sleeps 8
                                16

                                Confirmation within 24 hours

                                Your booking request will be confirmed or denied within 24 hours.

                                  • 2 BR
                                  • 2 BA
                                  • Sleeps 5
                                  19

                                  Confirmation within 24 hours

                                  Your booking request will be confirmed or denied within 24 hours.

                                    • 4 BR
                                    • 2 BA
                                    • Sleeps 9
                                    12

                                    Confirmation within 24 hours

                                    Your booking request will be confirmed or denied within 24 hours.

                                      • 4 BR
                                      • 3 BA
                                      • 2 HF BA
                                      • Sleeps 10
                                      9

                                      Confirmation within 24 hours

                                      Your booking request will be confirmed or denied within 24 hours.

                                        • 3 BR
                                        • 2 BA
                                        • Sleeps 6
                                        9

                                        Confirmation within 24 hours

                                        Your booking request will be confirmed or denied within 24 hours.

                                          • 3 BR
                                          • 3 BA
                                          • Sleeps 11
                                          5

                                          Confirmation within 24 hours

                                          Your booking request will be confirmed or denied within 24 hours.

                                            • 1 BR
                                            • 1 BA
                                            • Sleeps 4
                                            9

                                            Confirmation within 24 hours

                                            Your booking request will be confirmed or denied within 24 hours.

                                              • 4 BR
                                              • 4 BA
                                              • 2 HF BA
                                              • Sleeps 10
                                              3

                                              Confirmation within 24 hours

                                              Your booking request will be confirmed or denied within 24 hours.

                                                • 5 BR
                                                • 4 BA
                                                • 2 HF BA
                                                • Sleeps 16
                                                5

                                                Confirmation within 24 hours

                                                Your booking request will be confirmed or denied within 24 hours.

                                                  • 4 BR
                                                  • 3 BA
                                                  • 1 HF BA
                                                  • Sleeps 10
                                                  4

                                                  Confirmation within 24 hours

                                                  Your booking request will be confirmed or denied within 24 hours.

                                                    • 2 BR
                                                    • 2 BA
                                                    • Sleeps 4
                                                    11

                                                    Confirmation within 24 hours

                                                    Your booking request will be confirmed or denied within 24 hours.

                                                      • 1 BR
                                                      • 1 BA
                                                      • Sleeps 4
                                                      13

                                                      Confirmation within 24 hours

                                                      Your booking request will be confirmed or denied within 24 hours.

                                                        • 2 BR
                                                        • 2 BA
                                                        • 1 HF BA
                                                        • Sleeps 5
                                                        61

                                                        Confirmation within 24 hours

                                                        Your booking request will be confirmed or denied within 24 hours.

                                                          • 3 BR
                                                          • 2 BA
                                                          • Sleeps 8
                                                          1 Review

                                                          Confirmation within 24 hours

                                                          Your booking request will be confirmed or denied within 24 hours.

                                                            • 3 BR
                                                            • 2 BA
                                                            • 1 HF BA
                                                            • Sleeps 8
                                                            19

                                                            Confirmation within 24 hours

                                                            Your booking request will be confirmed or denied within 24 hours.

                                                              • 1 BR
                                                              • 1 BA
                                                              • Sleeps 3

                                                              Confirmation within 24 hours

                                                              Your booking request will be confirmed or denied within 24 hours.

                                                                • 3 BR
                                                                • 2 BA
                                                                • 1 HF BA
                                                                • Sleeps 7
                                                                8

                                                                Confirmation within 24 hours

                                                                Your booking request will be confirmed or denied within 24 hours.

                                                                  • 2 BR
                                                                  • 2 BA
                                                                  • Sleeps 4
                                                                  23

                                                                  Confirmation within 24 hours

                                                                  Your booking request will be confirmed or denied within 24 hours.

                                                                    • 3 BR
                                                                    • 2 BA
                                                                    • Sleeps 6
                                                                    17

                                                                    Confirmation within 24 hours

                                                                    Your booking request will be confirmed or denied within 24 hours.

                                                                      • 2 BR
                                                                      • 1 BA
                                                                      • 1 HF BA
                                                                      • Sleeps 4
                                                                      22

                                                                      Confirmation within 24 hours

                                                                      Your booking request will be confirmed or denied within 24 hours.

                                                                        • 1 BR
                                                                        • 1 BA
                                                                        • Sleeps 2
                                                                        43

                                                                        Confirmation within 24 hours

                                                                        Your booking request will be confirmed or denied within 24 hours.

                                                                          • 3 BR
                                                                          • 3 BA
                                                                          • Sleeps 10
                                                                          39

                                                                          Confirmation within 24 hours

                                                                          Your booking request will be confirmed or denied within 24 hours.

                                                                            • 3 BR
                                                                            • 2 BA
                                                                            • Sleeps 8
                                                                            7

                                                                            Confirmation within 24 hours

                                                                            Your booking request will be confirmed or denied within 24 hours.

                                                                              • 3 BR
                                                                              • 2 BA
                                                                              • Sleeps 6

                                                                              Confirmation within 24 hours

                                                                              Your booking request will be confirmed or denied within 24 hours.

                                                                                • 3 BR
                                                                                • 2 BA
                                                                                • 1 HF BA
                                                                                • Sleeps 8
                                                                                2 Reviews

                                                                                Confirmation within 24 hours

                                                                                Your booking request will be confirmed or denied within 24 hours.

                                                                                  • 4 BR
                                                                                  • 3 BA
                                                                                  • Sleeps 9
                                                                                  2 Reviews

                                                                                  Confirmation within 24 hours

                                                                                  Your booking request will be confirmed or denied within 24 hours.

                                                                                    • 5 BR
                                                                                    • 6 BA
                                                                                    • 1 HF BA
                                                                                    • Sleeps 14
                                                                                    27

                                                                                    Confirmation within 24 hours

                                                                                    Your booking request will be confirmed or denied within 24 hours.

                                                                                      • 2 BR
                                                                                      • 2 BA
                                                                                      • Sleeps 4
                                                                                      11

                                                                                      Confirmation within 24 hours

                                                                                      Your booking request will be confirmed or denied within 24 hours.

                                                                                        • 4 BR
                                                                                        • 3 BA
                                                                                        • Sleeps 8
                                                                                        59

                                                                                        Confirmation within 24 hours

                                                                                        Your booking request will be confirmed or denied within 24 hours.

                                                                                          • 3 BR
                                                                                          • 2 BA
                                                                                          • Sleeps 6
                                                                                          9

                                                                                          Confirmation within 24 hours

                                                                                          Your booking request will be confirmed or denied within 24 hours.

                                                                                            • 3 BR
                                                                                            • 2 BA
                                                                                            • 1 HF BA
                                                                                            • Sleeps 10
                                                                                            11

                                                                                            Confirmation within 24 hours

                                                                                            Your booking request will be confirmed or denied within 24 hours.

                                                                                              • 5 BR
                                                                                              • 4 BA
                                                                                              • Sleeps 17
                                                                                              12

                                                                                              Confirmation within 24 hours

                                                                                              Your booking request will be confirmed or denied within 24 hours.

                                                                                                • 5 BR
                                                                                                • 3 BA
                                                                                                • 1 HF BA
                                                                                                • Sleeps 11
                                                                                                7

                                                                                                Confirmation within 24 hours

                                                                                                Your booking request will be confirmed or denied within 24 hours.

                                                                                                  • 4 BR
                                                                                                  • 2 BA
                                                                                                  • Sleeps 8

                                                                                                  Confirmation within 24 hours

                                                                                                  Your booking request will be confirmed or denied within 24 hours.

                                                                                                    • 3 BR
                                                                                                    • 2 BA
                                                                                                    • 1 HF BA
                                                                                                    • Sleeps 7
                                                                                                    21

                                                                                                    Confirmation within 24 hours

                                                                                                    Your booking request will be confirmed or denied within 24 hours.

                                                                                                      • 4 BR
                                                                                                      • 1 BA
                                                                                                      • Sleeps 6
                                                                                                      7

                                                                                                      Confirmation within 24 hours

                                                                                                      Your booking request will be confirmed or denied within 24 hours.

                                                                                                      • 1 - 50 of 103